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KILINÇ H., Masullo M., D'Urso G., KARAYILDIRIM T., Alankus O., Piacente S.
PHYTOCHEMISTRY, vol.174, 2020 (SCI-Expanded)
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Publication Type:
Article / Article
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Volume:
174
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Publication Date:
2020
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Doi Number:
10.1016/j.phytochem.2020.112350
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Journal Name:
PHYTOCHEMISTRY
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Journal Indexes:
Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Analytical Abstracts, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Chimica, EMBASE, Food Science & Technology Abstracts, MEDLINE, Veterinary Science Database
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Keywords:
Scabiosa sicula, Caprifoliaceae, Triterpene-type saponins, Antioxidant activity, alpha-glucosidase inhibitory activity, LC-MS, TRITERPENE SAPONINS, CORYLUS-AVELLANA, PHARMACEUTICAL ETHNOBOTANY, ANTIOXIDANT, CONSTITUENTS, CATALONIA, PHENOLICS, DIARYLHEPTANOIDS, QUANTIFICATION, ELUCIDATION
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Dokuz Eylül University Affiliated:
Yes
Abstract
The genus Scabiosa (Caprifoliaceae) is represented by 80 species, widely used as medicinal plants for their positive effects on human diseases. On the basis of the interesting biological activity shown by Scabiosa spp., the phytochemical investigation of Scabiosa sicula L., never investigated before, was carried out. An initial LC-MS profile of the MeOH extract of S. sicula whole plant guided the isolation of 34 compounds, of which the structures were unambiguously elucidated by NMR analysis as phenolic compounds and triterpene saponins, among which eight undescribed compounds.