Phytochemical investigation of Scabiosa sicula guided by a preliminary HPLC-ESIMSn profiling

KILINÇ H., Masullo M., D'Urso G., KARAYILDIRIM T., Alankus O., Piacente S.

PHYTOCHEMISTRY, cilt.174, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 174
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1016/j.phytochem.2020.112350
  • Dergi Adı: PHYTOCHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Analytical Abstracts, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Chimica, EMBASE, Food Science & Technology Abstracts, MEDLINE, Veterinary Science Database
  • Anahtar Kelimeler: Scabiosa sicula, Caprifoliaceae, Triterpene-type saponins, Antioxidant activity, alpha-glucosidase inhibitory activity, LC-MS, TRITERPENE SAPONINS, CORYLUS-AVELLANA, PHARMACEUTICAL ETHNOBOTANY, ANTIOXIDANT, CONSTITUENTS, CATALONIA, PHENOLICS, DIARYLHEPTANOIDS, QUANTIFICATION, ELUCIDATION
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

The genus Scabiosa (Caprifoliaceae) is represented by 80 species, widely used as medicinal plants for their positive effects on human diseases. On the basis of the interesting biological activity shown by Scabiosa spp., the phytochemical investigation of Scabiosa sicula L., never investigated before, was carried out. An initial LC-MS profile of the MeOH extract of S. sicula whole plant guided the isolation of 34 compounds, of which the structures were unambiguously elucidated by NMR analysis as phenolic compounds and triterpene saponins, among which eight undescribed compounds.