Half-Dose Sugammadex After Neostigmine Versus Neostigmine as a Routine Reversal Agent: A Pilot Randomized Trial


Baysal A., SAĞIROĞLU G., Dogukan M., Ozkaynak I.

JOURNAL OF PERIANESTHESIA NURSING, vol.37, no.3, pp.326-332, 2022 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 37 Issue: 3
  • Publication Date: 2022
  • Doi Number: 10.1016/j.jopan.2021.09.009
  • Journal Name: JOURNAL OF PERIANESTHESIA NURSING
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus, CINAHL, EMBASE, MEDLINE, DIALNET
  • Page Numbers: pp.326-332
  • Keywords: sugammadex, neostigmine, neuromuscular blockade, residual neuromuscular blockade, postoperative complications
  • Dokuz Eylül University Affiliated: Yes

Abstract

Purpose: The use of sugammadex at a lower dose after a routine reversal dose of neostigmine may prevent residual neuromuscular blockade (rNMB). Our goal was to investigate the effects of the use of half-dose sugammadex for reversing rNMB after administration of neostigmine, and compare these effects to a routine full-dose of neostigmine.