Controlled Trial of Efficacy of Dexketoprofen in Sciatic Nerve Crush Injury in Rats

Kaptan H., Kasimcan O., Ayaz M., Bozdogan O., Karabagli H.

JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH, vol.31, no.1, pp.126-135, 2014 (SCI-Expanded, Scopus, TRDizin) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 1
  • Publication Date: 2014
  • Journal Name: JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.126-135
  • Keywords: Nerve injury, clipping, dexketoprofen trometamol, fiber diameter, axon number and nerve diameter
  • Dokuz Eylül University Affiliated: No

Abstract

Object: Local applications of Dexketoprofen trometamol (dex) have been shown to increase in the sciatic nerve functional tests following the nerve injuries. The aim of the current study was to compare the efficacy of dex application for 1 and 5 days following nerve injury rat model. Possible effects of dex were checked by means of the Sciatic Function Index (SFI), Withdrawal of the Reflex Leg (WRL), number of axons, axon diameter, and nerve diameters.