The effect of raloxifene on cardiac autonomic regulation in osteoporotic women

Got M., Baris N., Guneri S., Posaci C.

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, cilt.194, sa.5, ss.1249-1254, 2006 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 194 Sayı: 5
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1016/j.ajog.2005.12.004
  • Dergi Adı: AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1249-1254
  • Anahtar Kelimeler: raloxifene, autonomic regulation, menopause, osteoporosis
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Objective: There are suggestive data that raloxifene may have favorable effects on the arterial systems in postmenopausal women and thereby lowering the incidence of future adverse cardiovascular events. Reduction of heart rate variability appears to be a marker for identifying subjects with an increased risk for cardiac mortality, particularly in patients after myocardial infarction and in elderly people. Although there are conflicting data with regard to the effects of estrogen and progesterone on heart rate variability in postmenopausal women, the impact of raloxifene treatment on heart rate variability is fully unknown.