Akademik Veri Yönetim Sistemi
2025 Lipedema World Congress, Rome, İtalya, 5 - 08 Kasım 2025, ss.261, (Özet Bildiri)
Objectives: Pain is a common symptom among patients with lipedema. The mechanism of pain in lipedema is uncertain. The unclear nature of the pain adversely affects the diagnosis and treatment process. There is a lack of studies in the literature investigating whether the pain in lipedema patients is nociceptive or neuropathic. The aim of this study is to investigate whether the pain in lipedema has the character of neuropathic pain and to evaluate the effects of lipedema on patients’ quality of life and psychosocial status. Methods: The study included 43 patients diagnosed with lipedema and complaining of pain who applied to the Physical Medicine and Rehabilitation Outpatient Clinic, as well as a control group consisting of 42 patients diagnosed with acute subacromial impingement syndrome (SIS) and experiencing shoulder pain for less than 3 months as a nociceptive pain model. Patients’ pain characteristics were assessed using the LANSS Pain Scale and the PainDETECT Pain Questionnaire. Quality of life was evaluated using the Nottingham Health Profile. The presence of depression and anxiety was assessed using the Hospital Anxiety and Depression Scale questionnaires. Data were evaluated comparatively between the lipedema and control SIS groups. Results: 65.1% of lipedema patients were type 3 lipedema. 69.8% of patients were classified as Stage 2. There was no statistically significant difference between the groups in terms of age, height, education level, occupation, or presence of comorbidities (p>0.05). The mean BMI was statistically significantly higher in the lipedema group compared to the SIS group (p=0.03). LANSS and PainDETECT scores of lipedema group were found to be statistically significantly higher compared to the SIS group (p<0.001). According to the LANSS Pain Scale and PainDETECT Pain Questionnaire, prevalance of neuropathic pain in the lipedema group was significantly higher (p<0.001). There was no statistically significant correlation between the LANSS Pain Scale, PainDETECT Pain Questionnaire and symptom duration and lipedema stage (p>0.05). Nottingham Health Profile scores were significantly higher in the lipedema group, indicating lower quality of life compared to the SIS group (p<0.001). Conclusions: These findings suggest that neuropathic pain may be present in patients with lipedema, highlighting the importance of accurately identifying pain to improve quality of life and psychosocial well-being, as well as to facilitate diagnosis and treatment processes. Further studies are warranted to confirm these findings and explore potential therapeutic interventions for neuropathic pain in lipedema patients. Keywords: Lipedema, Neuropathic Pain, Acute Subacromial Impingement Syndrome