JOURNAL OF BASIC AND CLINICAL HEALTH SCIENCES, vol.5, no.2, pp.110-114, 2021 (ESCI)
Article / Article
JOURNAL OF BASIC AND CLINICAL HEALTH SCIENCES
Emerging Sources Citation Index (ESCI)
Brain tumors, glioblastoma, bevacizumab, apoptosis, drug resistance, NEWLY-DIAGNOSED GLIOBLASTOMA, RANDOMIZED PHASE-III, TEMOZOLOMIDE, RADIOTHERAPY, ANGIOGENESIS, RESISTANCE, TRIAL
Dokuz Eylül University Affiliated:
Aim: Glioblastoma multiforme (GBM) is the most malignant glial tumor. Angiogenesis which provides nutrient and oxygen support to proliferating cells plays an essential role in GBM development, proliferation, and metastasis. The development of antiangiogenetic agents is a promising treatment approach as blood vessels are essential for the vitality of tumor cells. For this purpose, in this study, the effects of bevacizumab on cell viability and apoptosis were analyzed using glioblastoma cells.