Akademik Veri Yönetim Sistemi
Turk Anesteziyoloji ve Reanimasyon Dernegi Dergisi, cilt.36, sa.4, ss.222-229, 2008 (Scopus)
We investigated the effects of desflurane anesthesia with high and low fresh gas flows on hemodynamic stability and desflurane consumption. After obtaining ethical comittee approval, 60 patients in the ASA risk groups I-II were included in the study. After anesthesia induction, the anesthesia maintenance was performed during the first 10 minutes with 4,4 L min -1 fresh gas flow and desflurane (4-6%) in all cases. The fresh gas flow was reduced to 1 L min-1 after 10 minutes whereas it was maintained as 4,4 L min-1 in Group N after the randomization of the patients into two groups. Heart rate (HR), mean arterial pressure (MAP), peripheral O2 saturation (SPO2), inspiratory desflurane (FiDes), expiratory desflurane (ETDes), inspiratory O2 (FiO 2), inspiratory CO2 (FiCO2), expiratory O 2 (ETO2), inspiratory N2O (FiN2O), expiratory N2O (ETN2O), end-tidal CO2 concentrations (ETCO2) and peak airway pressure (Pplateau) values were measured and recorded at 0., 2., 5., 7. and 10. minutes after intubation and every 5 minutes in first 60 minutes and every 15 minutes later on. The total amounts of fentanyl, desflurane, N2O and O2 were also recorded. There were no significant differences between the groups in terms of HR, MAP, FiDes, ETDes, ETCO2, Pplateau and total fentanyl consumption. The O2, N2O and desflurane consumptions of Group N were lower than those of Group N. (p<0.05) The desflurane consumption was 78 mL h-1 in group N and 26 mL h-1 in Group D. The hourly reduction rate of desflurane consumption was 67% in Group D. According to our results, we conclude that desflurane has provided an efficient anesthesia depth, hemodynamic stability and safe respiratory parameters in low flow anesthesia. Moreover, the low flow anesthesia with desflurane reduces the anesthetic costs when compared with high flow anesthesia by decreasing the total consumption of anesthetic gases.