Akademik Veri Yönetim Sistemi
Turk Anesteziyoloji ve Reanimasyon, cilt.28, sa.3, ss.162-165, 2000 (Scopus)
In this study we aimed to observe the systemic effects of intravesical lidocaine by measuring serum lidocaine level and haemodynamic changes during random vesical biopsy and cystoscotry. After institutional approval ASA II, III class 44 patient older than 60 years undergoing cystoscopy were recruited into the study. Urethral catheter was inserted following urethral anaesthesia with 2% lidocaine and fifty mL of 2% lidocaine was instilled via the catheter, MAP and HR were recorded in following 5 and 10 min to assess haemodynamic changes and surgery was performed. Additionally in 16 patient's serum lidocaine levels before, after and in 30 min following lidocaine administration were measured using EMIT (ensym multiple immunoassay). Before, after and in 30 min following lidocaine administration. Serum lidocaine levels were found to be negligible. MAP and HR measurements in 5 and 10 min were insignificant statistically. Patients with normal MAP; HR; and able to void were discharged if they had no pain, nausea and vomiting in the postoperative period. In this study, 50 mL 2% intravesical lidocaine administration was observed to be safe, without causing haemodynamic changes or other side effects.