Trichosporon asahii sepsis in a patient with pediatric malignancy
Journal of Microbiology, Immunology and Infection, vol.49, no.1, pp.146-149, 2016 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 49 Issue: 1
- Publication Date: 2016
- Doi Number: 10.1016/j.jmii.2013.01.003
- Journal Name: Journal of Microbiology, Immunology and Infection
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.146-149
- Keywords: Child, Sepsis, Trichosporon asahii
- Dokuz Eylül University Affiliated: No
Abstract
Trichosporon asahii is a rare opportunistic infection, especially in children, causing a life-threatening fungal infection underlying hematologic malignancies. Predisposing factors for infection with this pathogen are immunodeficiency including underlying malignancy, organ transplantation, extensive burns, human immunodeficiency virus infection, corticosteroid therapy, prosthetic valve surgery, and peritoneal dialysis. In the literature, a breakthrough under caspofungin, micafungin therapy is reported. In this article we report on a 16-year-old patient with Ewing sarcoma who had T. asahii sepsis. The patient died although he had been receiving caspofungin for less than 3 months and amphotericin B therapy for 3 days. A postmortem study of conchal tissues revealed T. asahii and mucormycosis histopathologically, and blood culture grew T. asahii.