Effect of sildenafil citrate on retinal functions: Preliminary report on Humphrey visual field analysis

Oner H., Aslan G., Kurtulan E., Ucar T., Saatci O., Esen A. A.

UROLOGIA INTERNATIONALIS, vol.73, no.1, pp.28-30, 2004 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 73 Issue: 1
  • Publication Date: 2004
  • Doi Number: 10.1159/000078800
  • Journal Name: UROLOGIA INTERNATIONALIS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.28-30
  • Keywords: erectile dysfunction, sildenafil citrate, visual field analysis, VIAGRA
  • Dokuz Eylül University Affiliated: Yes

Abstract

Objective: To assess the effect of sildenafil citrate treatment on visual field analysis (VFA) in patients using sildenafil citrate for erectile dysfunction. Materials and Methods: In this prospective study on 18 male volunteers with erectile dysfunction, bilateral VFA was performed using the Humphrey 30-2 central standard threshold test. White-on-white (W/W) and blue-on-yellow (B/Y) protocols were used prior to treatment ( baseline VFA) and after treatment (repeat VFA) with sildenafil citrate. W/W and B/Y baseline VFA and repeat VFA mean deviations (MD) were compared. Results: The baseline MD for W/W and B/Y protocols were -1.34 +/- 1.8 and -2.59 +/- 2.1 dB, respectively, whereas the mean repeat MD for W/W and B/Y protocols were -1.79 +/- 2.21 and -2.83 +/- 3.31 dB, respectively. There was no statistically significant difference between W/W and B/Y baseline and repeat VFA with respect to MD (p > 0.05). Conclusion: Sildenafil citrate causes no significant changes in Humphrey VFA in patients with erectile dysfunction. Copyright (C) 2004 S. Karger AG, Basel.