Is induction of fetal diuresis with intraamniotic furosemide effective for the removal of intestinal waste products from amniotic fluid?


HAKGÜDER F. G., Ates O., OLGUNER M., Sisman A., Akgur F.

EUROPEAN JOURNAL OF PEDIATRIC SURGERY, vol.12, no.5, pp.293-298, 2002 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 12 Issue: 5
  • Publication Date: 2002
  • Doi Number: 10.1055/s-2002-35958
  • Journal Name: EUROPEAN JOURNAL OF PEDIATRIC SURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.293-298
  • Keywords: gastroschisis, amniotic fluid, intestinal damage, intraamniotic furosemide, HUMAN NEONATAL URINE, EXPERIMENTAL GASTROSCHISIS, TRANSABDOMINAL AMNIOINFUSION, SEVERE OLIGOHYDRAMNIOS, DAMAGE, EXCHANGE, PREVENTION, BOWEL, MECONIUM, ETIOLOGY
  • Dokuz Eylül University Affiliated: Yes

Abstract

Aim: In gastroschisis, contact with amniotic fluid (AF) causes intestinal damage. Intraamniotic meconium has been shown. to be responsible for the intestinal damage, and intestinal damage has been shown to correlate with intraamniotic meconium concentrations. Intraamniotic meconium below a threshold level does not cause intestinal damage. Intraamniotic meconium concentrations can be lowered by AF exchange. Can induction of foetal diuresis by an intraamniotic injection of furosemide be used as an alternative method for the same purpose?