Pancreatic adenocarcinoma: detection and staging with dynamic MR imaging

BARLIK OBUZ F., Dicle O., Coker A., Sagol Ö., Karademir S.

EUROPEAN JOURNAL OF RADIOLOGY, cilt.38, sa.2, ss.146-150, 2001 (SCI-Expanded) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 38 Sayı: 2
  • Basım Tarihi: 2001
  • Doi Numarası: 10.1016/s0720-048x(00)00274-6
  • Dergi Adı: EUROPEAN JOURNAL OF RADIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.146-150
  • Anahtar Kelimeler: pancreatic carcinoma, magnetic resonance (MR), comparative studies, PHASE HELICAL CT, PREOPERATIVE ASSESSMENT, DUCTAL ADENOCARCINOMA, COMPUTED-TOMOGRAPHY, FAT-SUPPRESSION, CONTRAST, CANCER, RESECTABILITY, DIAGNOSIS, NEOPLASMS
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Objective: To compare the efficacy of dynamic contrast-enhanced MR imaging and spin-echo T1-weighted with and without fat-saturated MR imaging in the detection and staging of pancreatic adenocarcinoma. Methods and material: Spin-echo T1-weighted, fat-saturated T1-weighted and dynamic breath-hold 2D-FLASH MR imaging were performed in 25 patients with pancreatic adenocarcinoma. MR images were analysed by calculating the CNR between tumor and normal portion of the pancreas. The CNRs calculated at each sequences were compared. A total of 16 out of 25 patients underwent surgery. Preoperative staging according to TNM classification was also done in patients undergoing surgery. Results: The CNR was significantly different (P < 0.05) in the arterial phase of dynamic MR images. The accuracy of 'T' staging was 75% for SE T1-W, fat-saturated T1-W and arterial phase of dynamic MR images. Conclusion: The CNRs between pancreatic carcinoma and normal pancreas is significantly higher in dynamic MR sequences than the SE T1-W, fat-saturated T1-W sequences. However, the accuracy of tumor staging according to TNM is equivocal to SE T1-W and fat-saturated T1-W images. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.