Elevated serum neopterin levels in children with functional constipation: association with systemic proinflammatory cytokines

Cirali C., Ulusoy E., KÜME T., ARSLAN N.

WORLD JOURNAL OF PEDIATRICS, cilt.14, sa.5, ss.448-453, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 14 Sayı: 5
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1007/s12519-018-0144-8
  • Dergi Adı: WORLD JOURNAL OF PEDIATRICS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.448-453
  • Anahtar Kelimeler: Children, Constipation, Cytokine, Inflammation, Neopterin, IRRITABLE-BOWEL-SYNDROME, LOW-GRADE INFLAMMATION, URINARY NEOPTERIN, DISEASE, MARKER, CANCER, CALPROTECTIN, BIOMARKERS, RISK
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Background Functional constipation is a clinical problem with an incompletely understood etiology. Functional bowel diseases have been shown to be related to inflammation in many studies in adults. In this study, we aimed to evaluate leukocytes, C-reactive protein, proinflammatory and anti-inflammatory cytokines, and neopterin levels in children with functional constipation.