The Complex Genetic Landscape of Hereditary Ataxias in Turkey and Implications in Clinical Practice

Vural, Atay; Simsir, Gulsah; Tekgul, Seyma; Kocoglu, Cemile; Akcimen, Fulya; Kartal, Ece; Sen, Nesli; Lahut, Suna; Omur, Ozgur; Saner, Nazan; Gul, Tugce; Bayraktar, Elif; Palvadeau, Robin; Tunca, Ceren; Cetinkaya, Caroline; Eken, Asli; Sahbaz, Irmak; Koc, Muge; Cakmak, Ozgur; Hanagasi, Hasmet; Bilgic, Basar; Eraksoy, Mefkure; GÜNDÜZ, Ayşegül; APAYDIN, Hülya; KIZILTAN, Güneş; Ozekmekci, Sibel; SİVA, Aksel; Altintas, Ayse; KAYA GÜLEÇ, Zeynep; Parman, Yesim; Oflazer, Piraye; Deymeer, Feza; Durmus, Hacer; Sahin, Erdi; Cakar, Arman; Tufekcioglu, Zeynep; Tekturk, Pinar; Corbali, M.; Tireli, Hulya; AKDAL HALMAGYI, GÜLDEN; YİŞ, ULUÇ; Hiz, AYŞE; Sengun, İHSAN; BORA, ELÇİN; Serdaroglu, Gul; Ozbek, Sevda; AĞAN YILDIRIM, KADRİYE; GÜNAL, DİLEK; Us, Onder; Kurt, Semiha; AKSOY, DÜRDANE; Tokcaer, Ayse; ELMAS, MUHSİN; GÜLTEKİN, MURAT; KUMANDAŞ, SEFER; ACER, HAMİT; Ozcora, Gul; Yayla, Vildan; Soysal, Aysun; Genc, Gencer; Gulluoglu, Halil; Kotan, Dilcan; Ayas, Zeynep; Sahin, Huseyin; Tan, Ersin; Topcu, Meral; Topcuoglu, Esen; Akbostanci, Cenk; KOÇ, AYŞE; Ertan, Sibel; ELİBOL, BÜLENT; Basak, A.

doi:10.1002/mds.28518

The Complex Genetic Landscape of Hereditary Ataxias in Turkey and Implications in Clinical Practice

Vural A., Simsir G., Tekgul S., Kocoglu C., Akcimen F., Kartal E., ...More

MOVEMENT DISORDERS, vol.36, no.7, pp.1676-1688, 2021 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 36 Issue: 7
Publication Date: 2021
Doi Number: 10.1002/mds.28518
Journal Name: MOVEMENT DISORDERS
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CINAHL, EMBASE, MEDLINE
Page Numbers: pp.1676-1688
Keywords: ataxia, genetics, heterogeneity, whole&#8208, exome sequencing, Turkey
Dokuz Eylül University Affiliated: Yes

Abstract

Background The genetic and epidemiological features of hereditary ataxias have been reported in several populations; however, Turkey is still unexplored. Due to high consanguinity, recessive ataxias are more common in Turkey than in Western European populations.