The Complex Genetic Landscape of Hereditary Ataxias in Turkey and Implications in Clinical Practice

Vural A., Simsir G., Tekgul S., Kocoglu C., Akcimen F., Kartal E., ...More

MOVEMENT DISORDERS, vol.36, no.7, pp.1676-1688, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 36 Issue: 7
  • Publication Date: 2021
  • Doi Number: 10.1002/mds.28518
  • Journal Name: MOVEMENT DISORDERS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CINAHL, EMBASE, MEDLINE
  • Page Numbers: pp.1676-1688
  • Keywords: ataxia, genetics, heterogeneity, whole&#8208, exome sequencing, Turkey, DOMINANT CEREBELLAR ATAXIAS, SPINOCEREBELLAR ATAXIAS, FEATURES
  • Dokuz Eylül University Affiliated: Yes

Abstract

Background The genetic and epidemiological features of hereditary ataxias have been reported in several populations; however, Turkey is still unexplored. Due to high consanguinity, recessive ataxias are more common in Turkey than in Western European populations.