Mild cognitive impairment in Parkinson's disease is associated with decreased P300 amplitude and reduced putamen volume

Hunerli, Duygu; EMEK SAVAŞ, DERYA; Cavusoglu, Berrin; DÖNMEZ ÇOLAKOĞLU, BERRİL; ADA, EMEL; Yener, GÖRSEV

doi:10.1016/j.clinph.2019.04.314

Mild cognitive impairment in Parkinson's disease is associated with decreased P300 amplitude and reduced putamen volume

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Hunerli D., EMEK SAVAŞ D. D., Cavusoglu B., DÖNMEZ ÇOLAKOĞLU B., ADA E., Yener G.

CLINICAL NEUROPHYSIOLOGY, vol.130, no.8, pp.1208-1217, 2019 (SCI-Expanded)

Publication Type: Article / Article
Volume: 130 Issue: 8
Publication Date: 2019
Doi Number: 10.1016/j.clinph.2019.04.314
Journal Name: CLINICAL NEUROPHYSIOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.1208-1217
Keywords: Parkinson's disease, Mild cognitive impairment, Event-related potentials, P300, Volumetric MRI, Subcortical gray matter, EVENT-RELATED POTENTIALS, GREY-MATTER CHANGES, BASAL GANGLIA, SUBCORTICAL ATROPHY, DIAGNOSTIC-CRITERIA, ALZHEIMERS-DISEASE, EVOKED POTENTIALS, CEREBRAL ATROPHY, VISUAL P300, PROGRESSION
Dokuz Eylül University Affiliated: Yes

Abstract

Objective: Functional and structural brain alterations of cognitively normal Parkinson's disease (PD-CN) and Parkinson's disease mild cognitive impairment (PD-MCI) patients were investigated using event-related potentials (ERP) P300 and volumetric magnetic resonance imaging (MRI) parameters.