EVALUATION OF PREOPERATIVE COMPUTED TOMOGRAPHY IN STAGING PERITONEAL CARCINOMATOSIS PATIENTS


VARDAR B. U., AGALAR C., CANDA A., SOKMEN S., BARLIK OBUZ F.

İzmir Eğitim ve Araştırma Hastanesi Tıp Dergisi, cilt.25, sa.3, ss.251-258, 2021 (Hakemli Dergi) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 25 Sayı: 3
  • Basım Tarihi: 2021
  • Dergi Adı: İzmir Eğitim ve Araştırma Hastanesi Tıp Dergisi
  • Derginin Tarandığı İndeksler: TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.251-258
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Introduction: We aimed to investigate the accuracy of computed tomography (CT) and evaluate the interobserver correlation and agreement between two radiologists in preoperative staging of peritoneal carcinomatosis (PC) patients. Material and Method: Two blinded radiologists retrospectively evaluated preoperative CT scans of 48 patients with PC. According to the Sugarbaker classification, the peritoneal cancer index (PCI) was scored based on lesion size and distribution. Intraoperative findings were regarded as the gold standard. The results were analyzed by the Wilcoxon signed-rank, Spearman’s correlation, Kendall’s tau-b, and Cohen’s kappa tests. Results: The mean PCI score was 12.73 (±6.92) for surgery, 11.08 (±6.34) for Radiologist 1, and 10.56 (±6.49) for Radiologist 2. A comparison of total PCI scores showed a significant difference between surgical PCI scores and preoperative CT PCI scores (for both radiologists p=0.002). There was no significant difference between the two radiologists’ total scores (p=0.123) with a very strong correlation (rs=0.921, p<0.001). Both radiologists strongly correlated with intraoperative PCI (rs=0.860, p<0.001; rs=0.782, p<0.001). There was no significant difference between the two radiologists’ regional lesion sizes (p values range from 0.189 to 0.423). There were substantial to almost perfect agreements (κ=0.624-0.853, p <0.001) and moderate to strong correlations (τb=0.66- 0.83, p<0.001) between two radiologists’ regional PCI scores. Conclusion: CT is a consistent imaging technique in the preoperative staging of PC patients with its high interobserver correlation and agreement, although it underestimates intraoperative findings.