Effects of Serelaxin in Patients with Acute Heart Failure

Metra, Marco; Teerlink, John; Cotter, Gad; Davison, Beth; Felker, G.; Filippatos, Gerasimos; Greenberg, Barry; Pang, Peter; Ponikowski, Piotr; Voors, Adriaan; Adams, Kirkwood; Anker, Stefan; Arias-Mendoza, Alexandra; Avendano, Patricio; Bacal, Fernando; Boehm, Michael; Bortman, Guillermo; Cleland, John; Cohen-Solal, Alain; Crespo-Leiro, Maria; Dorobantu, Maria; Echeverria, Luis; Ferrari, Roberto; Goland, Sorel; Goncalvesova, Eva; Goudev, Assen; Kober, Lars; Lema-Osores, Juan; Levy, Phillip; Mcdonald, Kenneth; Manga, Pravin; Merkely, Bela; Mueller, Christian; Pieske, Burkert; Silva-Cardoso, Jose; Spinar, Jindrich; Squire, Iain; Stepinska, Janina; Van Mieghem, Walter; Von Lewinski, Dirk; Wikstrom, Gerhard; Yılmaz, MEHMET; Hagner, Nicole; Holbro, Thomas; Hua, Tsushung; Sabarwal, Shalini; Severin, Thomas; Szecsody, Peter; Gimpelewicz, Claudio

doi:10.1056/nejmoa1801291

Effects of Serelaxin in Patients with Acute Heart Failure

Atıf İçin Kopyala

Metra M., Teerlink J. R., Cotter G., Davison B. A., Felker G. M., Filippatos G., ...Daha Fazla

NEW ENGLAND JOURNAL OF MEDICINE, cilt.381, sa.8, ss.716-726, 2019 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 381 Sayı: 8
Basım Tarihi: 2019
Doi Numarası: 10.1056/nejmoa1801291
Dergi Adı: NEW ENGLAND JOURNAL OF MEDICINE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.716-726
Dokuz Eylül Üniversitesi Adresli: Evet

Özet

BackgroundSerelaxin is a recombinant form of human relaxin-2, a vasodilator hormone that contributes to cardiovascular and renal adaptations during pregnancy. Previous studies have suggested that treatment with serelaxin may result in relief of symptoms and in better outcomes in patients with acute heart failure.