Journal of endocrinological investigation, cilt.39, sa.7, ss.747-54, 2016 (SCI-Expanded)
Context Adropin is a peptide hormone implicated in the regulation of insulin sensitivity and energy homeostasis. Polycystic ovary syndrome (PCOS) is a metabolic and reproductive disease associated with insulin resistance. It has been demonstrated that various inflammatory markers increased in PCOS including TNF-alpha. TNF-alpha regulates the secretion of certain peptides which play a crucial role in glucose and lipid homeostasis. There is also some evidence of a link between TNF-alpha and adropin.