Prognostic value of the neutrophil-lymphocyte ratio in patients with ST-elevated acute myocardial infarction

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GAZİ E., BAYRAM B., Gazi S., Temiz A., KIRILMAZ B., Altun B., ...More

Clinical and Applied Thrombosis/Hemostasis, vol.21, no.2, pp.155-159, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 21 Issue: 2
  • Publication Date: 2015
  • Doi Number: 10.1177/1076029613492011
  • Journal Name: Clinical and Applied Thrombosis/Hemostasis
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.155-159
  • Keywords: acute coronary syndrome, blood cell count, leukocyte count, myocardial infarction, neutrophil-lymphocyte ratio, prognosis, BLOOD-CELL COUNT, CORONARY-HEART-DISEASE, LONG-TERM MORTALITY, NEUTROPHIL/LYMPHOCYTE RATIO, CARDIOVASCULAR-DISEASE, LEUKOCYTE COUNT, ASSOCIATION, RISK, INFLAMMATION, AMERICAN
  • Dokuz Eylül University Affiliated: Yes

Abstract

© The Author(s) 2012The predictive value of leukocyte counts has been reported in patients with acute myocardial infarction (AMI). We aimed to evaluate the predictive value of the total leukocyte count and neutrophil-lymphocyte (N/L) ratio for mortality due to AMI. A total of 522 patients with acute ST-elevated MI were included in the study. The study population was divided into tertiles based on admission N/L ratio values. High (n = 174) and low N/L (n = 348) ratio groups were defined as patients having values in the third tertile (>5.77) and lower 2 tertiles (≤5.77), respectively. The high N/L ratio group had a significantly higher incidence of in-hospital cardiovascular mortality (13.8% vs 4.6%, P < .001). An N/L ratio >5.77 was found to be an independent predictor of in-hospital cardiovascular mortality (hazard ratio: 3.78, 95% confidence interval: 1.71-8.30, P = .001). A high N/L ratio is a strong and independent predictor of in-hospital cardiovascular mortality of AMI with ST elevation.