Association between serum macrophage colony-stimulating factor levels and monocyte and thrombocyte counts in healthy, hypoxic, and septic term neonates
PEDIATRICS, cilt.108, sa.2, ss.329-332, 2001 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 108 Sayı: 2
- Basım Tarihi: 2001
- Doi Numarası: 10.1542/peds.108.2.329
- Dergi Adı: PEDIATRICS
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.329-332
- Anahtar Kelimeler: macrophage-colony-stimulating factor, thrombocytopenia, monocyte, sepsis, neonate
- Dokuz Eylül Üniversitesi Adresli: Evet
Özet
Objective. Macrophage colony-stimulating factor (M-CSF) is a hematopoietic growth factor that mainly stimulates the growth, differentiation, and proliferation of cells of the monocyte-macrophage lineage. There are only limited numbers of studies about M-CSF levels in neonates, but high levels of serum M-CSF have been reported in septic and some thrombocytopenic adult patients. In this study, we investigated the serum M-CSF levels in healthy, septic, and hypoxic term neonates on the first day of life and examined the relationship of serum M-CSF levels and circulating monocyte and thrombocyte counts in these newborn infants.