A Case Report of Synchronous Lung Adenocarcinoma and Systemic Mastocytosis

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Tarhan M. O.

Scholars Journal of Medical Case Reports, pp.1-5, 2024 (Peer-Reviewed Journal)

• Publication Type: Article / Case Report
• Publication Date: 2024
• Doi Number: 10.36347/sjmcr.2024.v12i08.00x
• Journal Name: Scholars Journal of Medical Case Reports
• Page Numbers: pp.1-5
• Dokuz Eylül University Affiliated: Yes

Abstract

Systemic mastocytosis(SM) is an extremely rare disease and is characterized by clonal proliferation of mast cells in any

part of the body. SM patients are prone to developing cancer. Although the relationship between lung adenocarcinoma

and SM is unclear, they share similar mutations. A female patient in her 40s presented with complaints of shoulder pain

and unexpected weight. Later, the patient was diagnosed with lung adenocarcinoma. Additionally, systemic

mastocytosis was detected while investigating her B symptoms and anemia. Induction chemotherapy with carboplatin

and paclitaxel was decided as initial treatment. She did not respond to 3 cycles of this chemotherapy regimen.

Radiotherapy with etoposide and cisplatin was applied as second-line treatment. Although the size of the lung

adenocarcinoma was stable, her anemia, shoulder pain, B symptoms, and cachexia improved after second-line treatment.

We present a case of synchronous lung adenocarcinoma and systemic mastocytosis presenting with B symptoms and

shoulder pain.

Keywords: Anemia, Lung Carcinoma, Systemic Mastocytosis, Synchronous.