Clinical Response to Adjunctive Pegylated Interferon Alpha-2a Treatment in Disseminated Mycobacterial Infection in Children with Complete IFNGR1 Deficiency: A Case Report
JOURNAL OF PEDIATRIC INFECTIOUS DISEASES, cilt.17, sa.05, ss.264-268, 2022 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 17 Sayı: 05
- Basım Tarihi: 2022
- Doi Numarası: 10.1055/s-0042-1749646
- Dergi Adı: JOURNAL OF PEDIATRIC INFECTIOUS DISEASES
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, Veterinary Science Database
- Sayfa Sayıları: ss.264-268
- Anahtar Kelimeler: interferon gamma receptor 1 (IFNGR1), interferon alpha-2a, Mendelian susceptibility to mycobacterial disease, child
- Dokuz Eylül Üniversitesi Adresli: Evet
Özet
Objective Interferon gamma receptor 1 (IFNGR1) deficiency is a primary immunodeficiency that causes systemic infections with weakly virulent nontuberculous mycobacteria, which are very difficult to control with combined antimycobacterial agents.