Clinical Response to Adjunctive Pegylated Interferon Alpha-2a Treatment in Disseminated Mycobacterial Infection in Children with Complete IFNGR1 Deficiency: A Case Report

ATAKUL, GİZEM; ATAY, ÖZGE; KARAOĞLU ASRAK, HATİCE; ERBAŞ, İREM; ASİLSOY, SUNA; BELET, NURŞEN; KANGALLI BOYACIOĞLU, ÖZGE; Kose, Seda; AL, SERDAR; UZUNER, NEVİN; KARAMAN, ÖZKAN

doi:10.1055/s-0042-1749646

Clinical Response to Adjunctive Pegylated Interferon Alpha-2a Treatment in Disseminated Mycobacterial Infection in Children with Complete IFNGR1 Deficiency: A Case Report

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ATAKUL G., ATAY Ö., KARAOĞLU ASRAK H., ERBAŞ İ. C., ASİLSOY S., BELET N., ...More

JOURNAL OF PEDIATRIC INFECTIOUS DISEASES, vol.17, no.05, pp.264-268, 2022 (SCI-Expanded)

Publication Type: Article / Article
Volume: 17 Issue: 05
Publication Date: 2022
Doi Number: 10.1055/s-0042-1749646
Journal Name: JOURNAL OF PEDIATRIC INFECTIOUS DISEASES
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, Veterinary Science Database
Page Numbers: pp.264-268
Keywords: interferon gamma receptor 1 (IFNGR1), interferon alpha-2a, Mendelian susceptibility to mycobacterial disease, child, GAMMA
Dokuz Eylül University Affiliated: Yes

Abstract

Objective Interferon gamma receptor 1 (IFNGR1) deficiency is a primary immunodeficiency that causes systemic infections with weakly virulent nontuberculous mycobacteria, which are very difficult to control with combined antimycobacterial agents.