Clinical Response to Adjunctive Pegylated Interferon Alpha-2a Treatment in Disseminated Mycobacterial Infection in Children with Complete IFNGR1 Deficiency: A Case Report


ATAKUL G., ATAY Ö., KARAOĞLU ASRAK H., ERBAŞ İ. C., ASİLSOY S., BELET N., ...Daha Fazla

JOURNAL OF PEDIATRIC INFECTIOUS DISEASES, cilt.17, sa.05, ss.264-268, 2022 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 17 Sayı: 05
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1055/s-0042-1749646
  • Dergi Adı: JOURNAL OF PEDIATRIC INFECTIOUS DISEASES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, Veterinary Science Database
  • Sayfa Sayıları: ss.264-268
  • Anahtar Kelimeler: interferon gamma receptor 1 (IFNGR1), interferon alpha-2a, Mendelian susceptibility to mycobacterial disease, child, GAMMA
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Objective Interferon gamma receptor 1 (IFNGR1) deficiency is a primary immunodeficiency that causes systemic infections with weakly virulent nontuberculous mycobacteria, which are very difficult to control with combined antimycobacterial agents.