Clinical Response to Adjunctive Pegylated Interferon Alpha-2a Treatment in Disseminated Mycobacterial Infection in Children with Complete IFNGR1 Deficiency: A Case Report

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ATAKUL G., ATAY Ö., KARAOĞLU ASRAK H., ERBAŞ İ. C., ASİLSOY S., BELET N., ...Daha Fazla

JOURNAL OF PEDIATRIC INFECTIOUS DISEASES, cilt.17, sa.05, ss.264-268, 2022 (SCI-Expanded)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 17 Sayı: 05
• Basım Tarihi: 2022
• Doi Numarası: 10.1055/s-0042-1749646
• Dergi Adı: JOURNAL OF PEDIATRIC INFECTIOUS DISEASES
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, Veterinary Science Database
• Sayfa Sayıları: ss.264-268
• Anahtar Kelimeler: interferon gamma receptor 1 (IFNGR1), interferon alpha-2a, Mendelian susceptibility to mycobacterial disease, child
• Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Objective Interferon gamma receptor 1 (IFNGR1) deficiency is a primary immunodeficiency that causes systemic infections with weakly virulent nontuberculous mycobacteria, which are very difficult to control with combined antimycobacterial agents.