Nilotinib Does Not Alter the Secretory Functions of Carotid Artery Endothelial Cells in a Prothrombotic or Antithrombotic Fashion

Katgi A., Sevindik O. G., Gokbulut A. A., ÖZSAN G. H., YÜKSEL F., Solmaz S. M., ...Daha Fazla

CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS, cilt.21, sa.7, ss.678-683, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21 Sayı: 7
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1177/1076029614550817
  • Dergi Adı: CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.678-683
  • Anahtar Kelimeler: nilotinib, endothelial cells, carotid artery, function, cell viability, CHRONIC MYELOID-LEUKEMIA, DISEASE, THERAPY, IMATINIB, EVENTS
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Background: There have been concerns about the possible prothrombotic effects of nilotinib, especially in patients having cardiovascular risk factors. The potential mechanism behind the increased risk of thromboembolic events is still not clear.