Alternative factors in differential diagnosis of infantile fibrosarcoma

Aktaş S., Diniz G., Ortaç R., YÖRÜKOĞLU K.

Turkish Journal of Cancer, cilt.34, sa.4, ss.150-155, 2004 (Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 34 Sayı: 4
  • Basım Tarihi: 2004
  • Dergi Adı: Turkish Journal of Cancer
  • Derginin Tarandığı İndeksler: Scopus, Academic Search Premier
  • Sayfa Sayıları: ss.150-155
  • Anahtar Kelimeler: Angiogenesis, Fibrous tumors, Ki-67, Mitosis, nm23
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

The aim of this study was to determine the role of nm23 expression, percentage of Ki-67 labelling, vascularisation, mitosis and histologic features such as pattern, cellularity and density of inflammatory cell infiltrate in differential diagnosis of fibrous tumors. Specimens of 16 fibrous tumor cases were studied: 6 infantile fibrosarcoma (IFS), 3 adult fibrosarcoma (AFS) and 7 benign fibrous proliferations. All findings were examined and correlated statistically. In conclusion, number of inflammatory cells, histologic pattern and age of the patient are helpful in differential diagnosis of IFS and AFS.