Validation of an In-House-Developed GC-MS Method for 5α-Cholestanol According to ISO 15189:2012 Requirements.

Coker C., Uysal S.

Laboratory medicine, 2021 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume:
  • Publication Date: 2021
  • Doi Number: 10.1093/labmed/lmab095
  • Journal Name: Laboratory medicine
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, EMBASE, MEDLINE
  • Keywords: cholestanol, GC-MS, measurement uncertainty, proficiency testing, clinical laboratory, method performance, CEREBROTENDINOUS XANTHOMATOSIS, QUALITY-CONTROL, DIAGNOSIS, LABORATORIES, CHOLESTANOL, UNCERTAINTY
  • Dokuz Eylül University Affiliated: Yes

Abstract

Objective: The aim of this study was to validate a gas chromatography-mass spectrometry (GC-MS) method for the measurement of 5 alpha-cholestanol in the clinical laboratory in agreement with ISO 15189:2012.