Validation of an In-House-Developed GC-MS Method for 5α-Cholestanol According to ISO 15189:2012 Requirements.


Coker C., Uysal S.

Laboratory medicine, vol.53, pp.278-284, 2022 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 53
  • Publication Date: 2022
  • Doi Number: 10.1093/labmed/lmab095
  • Journal Name: Laboratory medicine
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, EMBASE, MEDLINE
  • Page Numbers: pp.278-284
  • Keywords: cholestanol, GC-MS, measurement uncertainty, proficiency testing, clinical laboratory, method performance
  • Dokuz Eylül University Affiliated: Yes

Abstract

Objective: The aim of this study was to validate a gas chromatography-mass spectrometry (GC-MS) method for the measurement of 5 alpha-cholestanol in the clinical laboratory in agreement with ISO 15189:2012.