Akademik Veri Yönetim Sistemi
BMC ORAL HEALTH, ss.1-11, 2025 (SCI-Expanded, Scopus)
Abstract
Background: This study aimed to evaluate the shear bond strength (SBS) of glass ionomer cement (GIC) modified with fluoride-loaded chitosan nanoparticles when applied to both sound dentin and caries-affected dentin (CAD).
Methods: Methods: Sixty human molar teeth were randomly allocated into two main groups based on dentin condition: sound dentin and CAD. Each group was further divided into three subgroups, containing 10 specimens each, as follows: conventional GIC, chitosan-modified GIC (CH-GIC), and fluoride-loaded chitosan nanoparticlemodified GIC (NCH-GIC). The occlusal surfaces of the teeth were ground to expose dentin, creating a 3x3 mm dentin window. For subgroups 1, 2, and 3, the dentin surfaces remained untreated. In subgroups 4, 5, and 6, the dentin was subjected to a demineralization solution for 66 hours to simulate artificial carious lesions. Subsequently, the conventional and modified GICs were applied to the dentin surfaces, and SBS measurements were conducted. Statistical analysis was performed using one-way ANOVA, Tukey’s post hoc test, and Paired samples t-test.
Results: No significant differences in bond strength to sound dentin were found among the groups (p>0.05). However, bond strengths to CAD varied significantly (p<0.05) and the NCH-GIC showed notably higher SBS than conventional GIC (p<0.05). Conventional GIC had significantly lower shear bond to CAD compared to sound dentin (p<0.05) while the modified GICs showed no significant bond strength difference between the two dentin types (p>0.05).
Conclusions: Incorporating fluoride-loaded chitosan nanoparticles into glass ionomer cement significantly improved its bond strength to caries-affected dentin while maintaining comparable adhesion to sound dentin.
Keywords: Caries-affected dentin, chitosan, glass ionomer, nanochitosan, shear bond strength.