C-type natriuretic peptide is associated with the severity of Crimean-Congo hemorrhagic fever

Turkdogan K. A., Zorlu A., ENGİN A., Guven F. M. K., Polat M. M., TURGUT O. O., ...More

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, vol.16, no.8, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 16 Issue: 8
  • Publication Date: 2012
  • Doi Number: 10.1016/j.ijid.2012.04.009
  • Journal Name: INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: Crimean-Congo hemorrhagic fever, C-type natriuretic peptide, Risk stratification, VIRUS, UPDATE
  • Dokuz Eylül University Affiliated: No

Abstract

Background: Crimean-Congo hemorrhagic fever (CCHF) is characterized by vascular dysfunction, indicating the involvement of endothelial cells. C-type natriuretic peptide (CNP) plays a critical role in the coordination of vascular tone and is associated with the prognosis in critically ill patients such as those with sepsis and septic shock. We investigated whether CNP is related to the severity of CCHF.