The effect of extracorporeal electromagnetic shock waves on renal proximal tubular function

Kirkali Z., Kirkali G., Tahiri Y.

International Urology and Nephrology, vol.26, no.3, pp.255-257, 1994 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 26 Issue: 3
  • Publication Date: 1994
  • Doi Number: 10.1007/bf02768206
  • Journal Name: International Urology and Nephrology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.255-257
  • Dokuz Eylül University Affiliated: Yes


In order to investigate the effect of electromagnetic shock waves on proximal tubular renal function, we measured the urine levels of the lysosomal enzyme N-acetyl-beta-glucosaminidase (NAG) prior to, 1 hour, 1 day, and 1 week after extracorporeal electromagnetic lithotripsy (ESWL) in 50 patients with urinary stone disease. Mean NAG level which was 5.18+0.09 U/l prior to ESWL increased to 5.29+0.09 U/l in the first hour and to 10.7+0.19 U/l on the first day after ESWL (p<0.001). The level returned to pre-ESWL values one week after ESWL (5.27+0.09 U/l). These findings show that extracorporeal electromagnetic shock waves cause significant damage to the proximal tubular epithelium of the kidney; however, these changes return to normal in the first week. © 1994 Akadémiai Kiadó.