Resveratrol ameliorates 2,4-dinitrofluorobenzene-induced atopic dermatitis-like lesions through effects on the epithelium

Sozmen S. C., KARAMAN M., CİLAKER MIÇILI S., IŞIK S., Ayyildiz Z. A., BAĞRIYANIK H. A., ...Daha Fazla

PEERJ, cilt.4, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 4
  • Basım Tarihi: 2016
  • Doi Numarası: 10.7717/peerj.1889
  • Dergi Adı: PEERJ
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Treatment, Atopic dermatitis, Mice, Resveratrol, NF-KAPPA-B, KERATINOCYTE APOPTOSIS, ECZEMATOUS DERMATITIS, THERAPEUTIC TARGET, DOWN-REGULATION, SKIN BARRIER, MOUSE MODEL, IFN-GAMMA, INFLAMMATION, CELLS
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Background. Resveratrol is a natural polyphenol that exhibits anti-inflammatory effects. The aim of this study was to investigate the effects of resveratrol treatment on epithelium-derived cytokines and epithelial apoptosis in a murine model of atopic dermatitis-like lesions.