Which Rivastigmine Formula is Better for Heart in Elderly Patients With Alzheimer's Disease: Oral or Patch?


IŞIK A. T., Soysal P., Yay A.

AMERICAN JOURNAL OF ALZHEIMERS DISEASE AND OTHER DEMENTIAS, vol.29, no.8, pp.735-738, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 29 Issue: 8
  • Publication Date: 2014
  • Doi Number: 10.1177/1533317514536598
  • Journal Name: AMERICAN JOURNAL OF ALZHEIMERS DISEASE AND OTHER DEMENTIAS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.735-738
  • Keywords: rivastigmine patch, oral rivastigmine, Alzheimer's disease, arrhythmia, hypotension, elderly, TRANSDERMAL PATCH, DOUBLE-BLIND, QT INTERVAL, POPULATION, 6-MONTH
  • Dokuz Eylül University Affiliated: Yes

Abstract

Objective: Rivastigmine is commonly used for the treatment of Alzheimer's disease (AD). All cholinesterase inhibitors, including rivastigmine, may cause cardiac side effects. The aim of this study is to compare the electrocardiographic (ECG) and hypotensive effects of formulations of rivastigmine.