Turkiye Klinikleri J Radiol, vol.7, no.2, pp.88-95, 2014 (Peer-Reviewed Journal)
Functional magnetic resonance imaging (fMRI), which currently the most widely used method for brain mapping and researching the neural basis of human cognition, is a methodology for detecting the neural activity in the brain. The physical basis of fMRI depends to blood-oxygen-leveldependent (BOLD) contrast which derived from a mismatch of blood flow and oxygen metabolism during local neural activation. There are widespread fMRI applications in clinical ranging from fMRIguided neurosurgery, presymptomatic diagnosis and drug development to and individualization of therapies.