Second-line drug susceptibilities of multidirug-resistant Mycobacterium tuberculosis isolates in Aegean region - Turkey

ÖZKÜTÜK N., SÜRÜCÜOĞLU S., Gazi H., Coskun M., ÖZKÜTÜK A. A., Ozbakkaloglu B.

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.38, sa.3, ss.245-250, 2008 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 38 Sayı: 3
  • Basım Tarihi: 2008
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.245-250
  • Anahtar Kelimeler: Mycobacterium tuberculosis, multidrug-resistant tuberculosis (MDR-TB), second-line drugs, susceptibility tests, extensively drug-resistant tuberculosis (XDR-TB), STRAINS, RUSSIA
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Aim: The emergence of multidrug-resistant tuberculosis (MDR-TB) is increasing, and the standard short-course regimen used for the treatment of TB is likely to be ineffective against MDR-TB, leading to the need for second-line drugs. In such situations, drug susceptibility testing is necessary to select an appropriate treatment regimen. Unfortunately, there are few studies showing the pattern of the second-line drug resistance in Turkey. We aimed to analyze the resistance to second-line anti-tuberculosis drugs of MDR strains of Mycobacterium tuberculosis isolated from the Aegean region of Turkey.