Second-line drug susceptibilities of multidirug-resistant Mycobacterium tuberculosis isolates in Aegean region - Turkey

ÖZKÜTÜK N., SÜRÜCÜOĞLU S., Gazi H., Coskun M., ÖZKÜTÜK A. A., Ozbakkaloglu B.

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.38, no.3, pp.245-250, 2008 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 38 Issue: 3
  • Publication Date: 2008
  • Journal Name: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.245-250
  • Keywords: Mycobacterium tuberculosis, multidrug-resistant tuberculosis (MDR-TB), second-line drugs, susceptibility tests, extensively drug-resistant tuberculosis (XDR-TB), STRAINS, RUSSIA
  • Dokuz Eylül University Affiliated: Yes

Abstract

Aim: The emergence of multidrug-resistant tuberculosis (MDR-TB) is increasing, and the standard short-course regimen used for the treatment of TB is likely to be ineffective against MDR-TB, leading to the need for second-line drugs. In such situations, drug susceptibility testing is necessary to select an appropriate treatment regimen. Unfortunately, there are few studies showing the pattern of the second-line drug resistance in Turkey. We aimed to analyze the resistance to second-line anti-tuberculosis drugs of MDR strains of Mycobacterium tuberculosis isolated from the Aegean region of Turkey.