Assessment of ex-vivo efficacy (oncogram) of immunotherapeutic and chemotherapeutic agents in bladder cancer: A pilot study of personalized treatment


Celik S., Sari H., MUNGAN M. U., YÖRÜKOĞLU K., ÇELEBİ İ., AKTAŞ S.

JOURNAL OF BUON, vol.25, no.1, pp.295-301, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 25 Issue: 1
  • Publication Date: 2020
  • Journal Name: JOURNAL OF BUON
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Page Numbers: pp.295-301
  • Keywords: Bacillus Calmette Guerin (BCG), bladder cancer, cell culture, gemcitabine, interferon-a (IFN-a), oncogram, RADICAL CYSTECTOMY, EXFOLIATED CELLS, IN-VITRO, TUMOR, RECURRENCE, CULTURE, IMPLANTATION, PROGRESSION, CARCINOMA, GRADE
  • Dokuz Eylül University Affiliated: Yes

Abstract

Purpose: To investigate the ex-vivo efficacy of immunotherapeutics and chemotherapeutics in bladder cancer primary cell cultures, to assess the applicability of the method according to the results and to evaluate suitability of the oncogram method for personalized treatment of bladder cancer.