A rare side effect of metformin: Metformin-induced hepatotoxicity

Aksay E., YANTURALI S., BAYRAM B., HOCAOĞLU AKSAY N., Kiyan S.

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.37, no.3, pp.173-175, 2007 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 37 Issue: 3
  • Publication Date: 2007
  • Journal Name: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.173-175
  • Keywords: metformin, metformin-associated lactic acidosis, hepatotoxicity, side effect, LACTIC-ACIDOSIS
  • Dokuz Eylül University Affiliated: Yes

Abstract

Metformin is an oral hypoglycemic agent that is commonly used in the treatment of type 2 diabetes mellitus. While metformin-associated metabolic acidosis is a widely recognized side effect of this drug, metformin-induced hepatotoxicity has been rarely reported in the literature. We present herein the case of a 52-year-old male in whom metformin-associated lactic acidosis and metformin-induced hepatotoxicity developed.