A rare side effect of metformin: Metformin-induced hepatotoxicity

Aksay E., YANTURALI S., BAYRAM B., HOCAOĞLU AKSAY N., Kiyan S.

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.37, sa.3, ss.173-175, 2007 (SCI-Expanded, Scopus, TRDizin) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 37 Sayı: 3
  • Basım Tarihi: 2007
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.173-175
  • Anahtar Kelimeler: metformin, metformin-associated lactic acidosis, hepatotoxicity, side effect
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Metformin is an oral hypoglycemic agent that is commonly used in the treatment of type 2 diabetes mellitus. While metformin-associated metabolic acidosis is a widely recognized side effect of this drug, metformin-induced hepatotoxicity has been rarely reported in the literature. We present herein the case of a 52-year-old male in whom metformin-associated lactic acidosis and metformin-induced hepatotoxicity developed.