Resveratrol and Cardiovascular System

SAYIN O., ARSLAN N., Guner G.

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.33, sa.3, ss.117-121, 2008 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 33 Sayı: 3
  • Basım Tarihi: 2008
  • Dergi Adı: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.117-121
  • Anahtar Kelimeler: Oxidative stress, endothelium, resveratrol, HYPOXIA-REOXYGENATION, ENDOTHELIAL FUNCTION, INJURY, BIOAVAILABILITY, ANTIOXIDANTS, REPERFUSION, METABOLISM, TRANSPORT, ISCHEMIA, AGENT
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Oxidative stres, characterized by an increased endogenous production of reactive oxygen species such as superoxide anion and hydrogen peroxide, is the basic cause of endothelial dysfunction. Oxidative stress has been implicated in the pathogenesis of cardiovascular disease, cancer, neurological disorders, diabetes, ageing and other diseases. There is increasing evidence that reactive oxygen species play a role in reoxygenation injury. Defense mechanisms against free radical-induced oxidative stress involve inhibition of these mechanisms, repair mechanisms, physical defense and antioxidant defense.