Influence of high-dose methotrexate therapy on the primordial follicles of the mouse ovary

Gol M., Saygili U., KOYUNCUOĞLU ÜLGÜN M., Uslu T.

JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH, cilt.35, sa.3, ss.429-433, 2009 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 35 Sayı: 3
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1111/j.1447-0756.2008.00945.x
  • Dergi Adı: JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.429-433
  • Anahtar Kelimeler: methotrexate, mice, ovary
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Objective: High-dose methotrexate (MTX) is one of the most prescribed agents in many malignant diseases affecting girls and young women of reproductive ages. This animal study directly measures the primordial follicle loss following exposure to high-dose MTX.