Evaluation of Serum Brain-Derived Neurotrophic Factor Levels in Children with Attention Deficit Hyperactivity Disorder: Preliminary Data

Sargin E., AKAY A., Resmi H., Alsen Cengizhan S., Ozek H., ELLİDOKUZ H., ...Daha Fazla

NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY, cilt.49, sa.2, ss.96-101, 2012 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 49 Sayı: 2
  • Basım Tarihi: 2012
  • Doi Numarası: 10.4274/npa.y5958
  • Dergi Adı: NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.96-101
  • Anahtar Kelimeler: Brain-derived neurotrophic factor, attention deficit hyperactivity disorder, children, neurotrophin, FACTOR EXPRESSION, BLOOD-BRAIN, RAT-BRAIN, BDNF, ADHD, DOPAMINE, CELLS, NEURONS, MICE, INFLAMMATION
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Objective: Brain-derived neurotrophic factor (BDNF) has an important role in the survival, differentiation and synaptic plasticity of a series of neuronal systems including dopaminergic neurons. For this reason, it is proposed that BDNF plays a role in the attention deficit hyperactivity disorder (ADHD) pathophysiology. In this study, serum BDNF levels in children diagnosed with ADHD were compared with those in healthy subjects.