Targeting Replicative Stress and DNA Repair by Combining PARP and Wee1 Kinase Inhibitors Is Synergistic in Triple Negative Breast Cancers with Cyclin E or BRCA1 Alteration

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Chen X., Yang D., Carey J. P. W., Karakas C., Albarracin C., Sahin A. A., ...More

CANCERS, vol.13, no.7, 2021 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 13 Issue: 7
  • Publication Date: 2021
  • Doi Number: 10.3390/cancers13071656
  • Journal Name: CANCERS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, CINAHL, EMBASE, Veterinary Science Database, Directory of Open Access Journals
  • Keywords: cyclin E, low molecular weight cyclin E (LMWE) PARP, Wee1 kinase, DNA replication stress, BRCA, SYNTHETIC LETHALITY, MITOTIC CATASTROPHE, MUTATIONS, EXPRESSION, DAMAGE, OVEREXPRESSION, AMPLIFICATION, COMBINATION, PROGNOSIS, OLAPARIB
  • Dokuz Eylül University Affiliated: Yes

Abstract

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