A Turkish 3-center study evaluation of serum folic acid and vitamin B12 levels in Alzheimer disease


Ulusu N. N., Yilmaz G., Erbayraktar Z., EVLİCE A. T., Aras S., Yener G., ...More

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.45, no.5, pp.1159-1166, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 45 Issue: 5
  • Publication Date: 2015
  • Doi Number: 10.3906/sag-1406-136
  • Journal Name: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.1159-1166
  • Keywords: Alzheimer disease, vitamin B12, folic acid, COGNITIVE DECLINE, DEMENTIA, PLAQUES, PROTEIN, BRAIN
  • Dokuz Eylül University Affiliated: Yes

Abstract

Background/aim: Alzheimer disease, a common proteopathy of advanced age, is characterized by cortical atrophy, neuron degeneration, neuronal loss, and accumulation of extracellular amyloid beta plaques. We aimed to investigate serum vitamin B12 and folic acid levels in Alzheimer disease and other dementia patients, as a potential screening test to detect presymptomatic Alzheimer disease in Turkish patients.