Protective effects of pentoxifylline on lipopolysaccharide-induced white matter injury in a rat model of periventricular leukomalasia

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Dilek M., KUMRAL A., Okyay E., ÖZBAL S., TUĞYAN K., Tuzun F., ...More

JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE, vol.26, no.18, pp.1865-1871, 2013 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 26 Issue: 18
• Publication Date: 2013
• Doi Number: 10.3109/14767058.2013.798290
• Journal Name: JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.1865-1871
• Keywords: Apoptosis, cytokines, maternal, myelin, newborn, ISCHEMIC BRAIN-INJURY, INTRAUTERINE INFLAMMATION, CELL-DEATH, OLIGODENDROCYTE, MICE, EXPOSURE, BIRTH
• Dokuz Eylül University Affiliated: Yes

Abstract

Objective: To investigate the potential neuroprotective effect of maternal pentoxifylline (PNTX) treatment in endotoxin-induced periventricular leukomalasia (PVL) in the developing rat brain.