Nucleic Acids for Electrochemical Biosensor Technology

Uygun Z. O., Ertuğrul Uygun H. D., Girgin Sağın F.

in: Biosensor-Current and Novel Strategies for Biosensing, Luis Jesús Villarreal-Gómez, Editor, Intechopen, London, pp.21-35, 2021

  • Publication Type: Book Chapter / Chapter Vocational Book
  • Publication Date: 2021
  • Publisher: Intechopen
  • City: London
  • Page Numbers: pp.21-35
  • Editors: Luis Jesús Villarreal-Gómez, Editor
  • Dokuz Eylül University Affiliated: Yes

Abstract

Biosensor technology has developed extremely rapidly in recent years. This

technology brings along precise measurements as well as specific measurements.

Thanks to its ability to be miniaturized and be easily accessible to the end user, it

is one-step ahead of other similar methods. The selectivity of biological molecules

and the sensitivity of electrochemical methods enable the continuous evolvement

of these new technologies. In this chapter, the use of nucleic acids as both recognition

agents and target molecules, the way they are used in biosensor technology and

their electrical properties are explained in detail with examples. Aptamers, which

are synthetic nucleic acids, and their use in electrochemical biosensor systems

with different electrochemical and immobilization methods have been compared

extensively.