Comparison of the efficacy of once- and twice-daily colchicine dosage in pediatric patients with familial Mediterranean fever - a randomized controlled noninferiority trial

Polat, Adem; Acikel, Cengizhan; Sozeri, Betul; DURSUN, İSMAİL; KASAPÇOPUR, Özgür; Gulez, Nesrin; Simsek, Dogan; Saldir, Mehmet; Dokurel, Ipek; Poyrazoglu, Hakan; Bakkaloglu, Sevcan; DELİBAŞ, ALİ; Ekinci, Zelal; AKTAY AYAZ, Nuray; Kandur, Yasar; PERU, HARUN; Kurt, Yasemin; Polat, Safiye; Unsal, ŞEVKET; Makay, BALAHAN; Gok, Faysal; ÖZEN, SEZA; Demirkaya, Erkan

doi:10.1186/s13075-016-0980-7

Comparison of the efficacy of once- and twice-daily colchicine dosage in pediatric patients with familial Mediterranean fever - a randomized controlled noninferiority trial

Polat A., Acikel C., Sozeri B., DURSUN İ., KASAPÇOPUR Ö., Gulez N., ...More

ARTHRITIS RESEARCH & THERAPY, vol.18, 2016 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 18
Publication Date: 2016
Doi Number: 10.1186/s13075-016-0980-7
Journal Name: ARTHRITIS RESEARCH & THERAPY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Keywords: Familial Mediterranean fever, Pediatric, Colchicine, Dosage schema
Open Archive Collection: AVESIS Open Access Collection
Dokuz Eylül University Affiliated: Yes

Abstract

Background: In this study, we examined the efficacy and safety of a once-daily dosage schema of colchicine compared with a twice-daily dosage schema in pediatric patients with familial Mediterranean fever (FMF).