High serum neurotensin level in obese adolescents is not associated with metabolic parameters, hyperphagia or food preference.

Cingoz G., ÖZYURT G., Uzun H., Doruk Ö., KÜME T., DÜNDAR B. N., ...More

Journal of pediatric endocrinology & metabolism : JPEM, vol.34, no.8, pp.971-978, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 34 Issue: 8
  • Publication Date: 2021
  • Doi Number: 10.1515/jpem-2021-0031
  • Journal Name: Journal of pediatric endocrinology & metabolism : JPEM
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, CAB Abstracts, EMBASE, MEDLINE
  • Page Numbers: pp.971-978
  • Keywords: binge eating disorder, food preference, hyperphagia, neurotensin, obesity, BODY-MASS INDEX, GASTRIC BYPASS, PERIPHERAL NEUROTENSIN, JEJUNOILEAL BYPASS, EATING-DISORDERS, CHILDREN, WEIGHT, BEHAVIOR, LEPTIN, PRONEUROTENSIN
  • Dokuz Eylül University Affiliated: Yes

Abstract

Objectives: Obesity is often the result of a high-calorie and unbalanced diet for a long time and can sometimes be associated with hyperphagia and eating disorders. Neurotensin (NT) is an anorexigenic peptide, which is secreted from the central nervous system and intestines, and increases intestinal fat absorption. In the literature, conflicting results regarding serum NT level in obesity and the relation of NT with metabolic parameters were reported. Besides, there is no data regarding the relation of NT with eating disorders or food preference in obese individuals. We aimed to evaluate the relation of serum NT level with metabolic parameters, hyperphagia, binge eating disorder (BED) and food preference in obese adolescents.