Taxane-based adjuvant chemotherapy reduces endothelin-1 and symmetric dimethylarginine levels in patients with breast cancer

Alacacioglu, A.; Kebapcilar, L.; SARI, İSMAİL; Gokgoz, Z.; Tarhan, MUSTAFA; Somali, I.; Yuksel, A.; Bozkaya, G.; Sop, G.

Taxane-based adjuvant chemotherapy reduces endothelin-1 and symmetric dimethylarginine levels in patients with breast cancer

Alacacioglu A., Kebapcilar L., SARI İ., Gokgoz Z., Tarhan O., Somali I., ...Daha Fazla

JOURNAL OF BUON, cilt.15, sa.3, ss.572-576, 2010 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 15 Sayı: 3
Basım Tarihi: 2010
Dergi Adı: JOURNAL OF BUON
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.572-576
Anahtar Kelimeler: adjuvant chemotherapy, asymmetric dimethylarginine, breast cancer, endothelin-1, taxanes
Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

Purpose: To evaluate the levels of asymmetric dimethylarginine (ADMA), an endothelin and nitric oxide (NO) synthase inhibitor, in patients with node-positive breast cancer who had undergone surgery and in a control group including healthy individuals. The effects of taxane-based chemotherapy on endothelin-1 (ET-1) and ADMA levels in the patient group were also studied.