Taxane-based adjuvant chemotherapy reduces endothelin-1 and symmetric dimethylarginine levels in patients with breast cancer

Alacacioglu A., Kebapcilar L., SARI İ., Gokgoz Z., Tarhan O., Somali I., ...More

JOURNAL OF BUON, vol.15, no.3, pp.572-576, 2010 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 15 Issue: 3
  • Publication Date: 2010
  • Journal Name: JOURNAL OF BUON
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.572-576
  • Keywords: adjuvant chemotherapy, asymmetric dimethylarginine, breast cancer, endothelin-1, taxanes, ASYMMETRIC DIMETHYLARGININE, MARKER, ADMA, AXIS
  • Dokuz Eylül University Affiliated: No

Abstract

Purpose: To evaluate the levels of asymmetric dimethylarginine (ADMA), an endothelin and nitric oxide (NO) synthase inhibitor, in patients with node-positive breast cancer who had undergone surgery and in a control group including healthy individuals. The effects of taxane-based chemotherapy on endothelin-1 (ET-1) and ADMA levels in the patient group were also studied.