Taxane-based adjuvant chemotherapy reduces endothelin-1 and symmetric dimethylarginine levels in patients with breast cancer
JOURNAL OF BUON, cilt.15, sa.3, ss.572-576, 2010 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 15 Sayı: 3
- Basım Tarihi: 2010
- Dergi Adı: JOURNAL OF BUON
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.572-576
- Anahtar Kelimeler: adjuvant chemotherapy, asymmetric dimethylarginine, breast cancer, endothelin-1, taxanes
- Dokuz Eylül Üniversitesi Adresli: Hayır
Özet
Purpose: To evaluate the levels of asymmetric dimethylarginine (ADMA), an endothelin and nitric oxide (NO) synthase inhibitor, in patients with node-positive breast cancer who had undergone surgery and in a control group including healthy individuals. The effects of taxane-based chemotherapy on endothelin-1 (ET-1) and ADMA levels in the patient group were also studied.