THE ROLE OF TRH-STIMULATED PROLACTIN RESPONSES IN DISTINGUISHING GONADOTROPIN-DEFICIENCY FROM CONSTITUTIONAL DELAYED PUBERTY


BUYUKGEBIZ A., OKTAY S.

JOURNAL OF PEDIATRIC ENDOCRINOLOGY, vol.7, no.4, pp.325-330, 1994 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 7 Issue: 4
  • Publication Date: 1994
  • Doi Number: 10.1515/jpem.1994.7.4.325
  • Journal Name: JOURNAL OF PEDIATRIC ENDOCRINOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.325-330
  • Keywords: CONSTITUTIONAL DELAYED PUBERTY, HYPOGONADOTROPIC HYPOGONADISM, PROLACTIN RESPONSE TO TRH, THYROTROPIN-RELEASING-HORMONE, HYPOGONADISM, DIAGNOSIS, MALES
  • Dokuz Eylül University Affiliated: No

Abstract

LHRH and TRH tests were performed in 16 boys age 14.5-18.5 years with constitutional delayed puberty (CDP); 9 idiopathic hypogonadotropic hypogonadism (IHH) males, age 15.0-22.0 years; and 7 control subjects age 14.5-19.5 years. The responses of FSH and LH to LHRH stimulation overlapped so that it was difficult to differentiate IHH from CDP. Some patients with IHH had normal gonadotropin responses.