TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.40, sa.2, ss.271-277, 2010 (SCI-Expanded)
Aim: Prolonged duration of nocturnal melatonin increase has been implicated in the pathogenesis of the seasonal affective disorder (SAD) winter depression. This study was designed to investigate behavioral and physiological consequences of constant dark exposure in male rats for its potential application to human affective disorders.