Exposure to continuous darkness leads to atypical symptoms of seasonal affective disorder in rats

Isman C. A., Toyran N., Gundogan N. U.

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.40, sa.2, ss.271-277, 2010 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 40 Sayı: 2
  • Basım Tarihi: 2010
  • Doi Numarası: 10.3906/sag-0803-26
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.271-277
  • Anahtar Kelimeler: Seasonal affective disorder, melatonin, constant darkness, FST, sucrose preference, BEHAVIORAL DESPAIR, MELATONIN, LIGHT, DEPRESSION
  • Dokuz Eylül Üniversitesi Adresli: Hayır

Özet

Aim: Prolonged duration of nocturnal melatonin increase has been implicated in the pathogenesis of the seasonal affective disorder (SAD) winter depression. This study was designed to investigate behavioral and physiological consequences of constant dark exposure in male rats for its potential application to human affective disorders.