Day-Time Isoflurane Administration Suppresses Circadian Gene Expressions in Both the Brain and a Peripheral Organ, Liver

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Gokmen N., Baris I., ÖÇMEN E., YILMAZ O., Gunerli A., Kavakli I. H.

TURKISH JOURNAL OF ANAESTHESIOLOGY AND REANIMATION, vol.45, no.4, pp.197-202, 2017 (ESCI)

• Publication Type: Article / Article
• Volume: 45 Issue: 4
• Publication Date: 2017
• Doi Number: 10.5152/tjar.2017.68466
• Journal Name: TURKISH JOURNAL OF ANAESTHESIOLOGY AND REANIMATION
• Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
• Page Numbers: pp.197-202
• Keywords: Anaesthesia, circadian rhythm, clock genes, isoflurane, INHALATION ANESTHESIA, MELATONIN SECRETION, SURGERY, CLOCK, TIME, RATS, SEVOFLURANE, PROPOFOL, RHYTHMS
• Dokuz Eylül University Affiliated: Yes

Abstract

Objective: The aim of this study is to investigate the effects of light and administration time of isoflurane on circadian gene expression in the brains and liver tissues of rats kept in light-dark cycle.