beta-Tubulin mRNA Expression Profiles During Long-Term Memory Formation in Classically Conditioned C. Elegans
JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH, vol.30, no.2, pp.296-304, 2013 (SCI-Expanded, TRDizin)
- Publication Type: Article / Article
- Volume: 30 Issue: 2
- Publication Date: 2013
- Journal Name: JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), TR DİZİN (ULAKBİM)
- Page Numbers: pp.296-304
- Keywords: C. elegans, learning, memory, long-term memory, classical conditioning, tubulin, NEMATODE CAENORHABDITIS-ELEGANS, GLUTAMATE-RECEPTOR, PROTEIN-SYNTHESIS, APLYSIA, NEURONS, SENSITIZATION, HABITUATION, FACILITATION, CHEMOTAXIS, GENETICS
- Dokuz Eylül University Affiliated: No
Abstract
We report on the mRNA expression profiles of beta-tubulin genes in Caenorhabditis elegans during the process of classical conditioning, a type of associative learning. In this research, based on the model that suggests the formation of new synaptic connections for long-term memory storage by means of cytoskeletal rearrangement, we measure the expressional changes on the beta-tubulin mRNA levels via quantitative real-time PCR. Using this method, we find that beta-tubulin mRNA levels do not significantly change in C. elegans during classical conditioning and long-term memory formation process.