The Role of Cytochrome P450 3A5 Enzyme on the Metabolism of Tacrolimus in Rats

Gur O., GÜMÜŞTEKİN M., Murat N., Gidener S.

JOURNAL OF BASIC AND CLINICAL HEALTH SCIENCES, cilt.1, sa.2, ss.53-56, 2017 (ESCI, TRDizin)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 1 Sayı: 2
  • Basım Tarihi: 2017
  • Doi Numarası: 10.5152/jbachs.2017.84
  • Dergi Adı: JOURNAL OF BASIC AND CLINICAL HEALTH SCIENCES
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.53-56
  • Anahtar Kelimeler: AUC, CYP3A5, drug metabolism, rat, tacrolimus
  • Dokuz Eylül Üniversitesi Adresli: Evet

Özet

Purpose: The present study was designed to determine the effect ratio of CYP3A5 on the metabolism of tacrolimus that is used as an immunosuppressant for tissue transplantation.