Copy For Citation
Gur O., GÜMÜŞTEKİN M., Murat N., Gidener S.
JOURNAL OF BASIC AND CLINICAL HEALTH SCIENCES, vol.1, no.2, pp.53-56, 2017 (ESCI)
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Publication Type:
Article / Article
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Volume:
1
Issue:
2
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Publication Date:
2017
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Doi Number:
10.5152/jbachs.2017.84
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Journal Name:
JOURNAL OF BASIC AND CLINICAL HEALTH SCIENCES
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Journal Indexes:
Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
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Page Numbers:
pp.53-56
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Keywords:
AUC, CYP3A5, drug metabolism, rat, tacrolimus, MECHANISM-BASED INACTIVATION, HIV PROTEASE INHIBITORS, P-GLYCOPROTEIN, LIVER-TRANSPLANTATION, BLOOD-CONCENTRATION, PHARMACOKINETICS, MICROSOMES, INDINAVIR, RITONAVIR, POLYMORPHISMS
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Dokuz Eylül University Affiliated:
Yes
Abstract
Purpose: The present study was designed to determine the effect ratio of CYP3A5 on the metabolism of tacrolimus that is used as an immunosuppressant for tissue transplantation.