Journal of Rheumatology and Medical Rehabilitation, cilt.10, sa.3, ss.151-155, 1999 (Scopus, TRDizin)
The aim of this study was to evaluate the efficacy of botulinum toxin A in reducing spasticity and improving function in hemiplegic upper limb. 11 hemiplegic patients were included in the study. Botulinum toxin A injected into the arm and forearm flexor muscles. Patients were examined before injection and 5 day, 2 weeks, 4 weeks, 8 weeks, 12 weeks, 16 weeks after injection. Muscle tone of elbow, wrist, metacarpophalangeal and interphalengeal joints was rated by modified Ashworth scale. The range of shoulder, elbow, wrist and metacarpophalangeal joints active and passive movements were measured with goniometer. Hand hygiene score, finger position score at rest, Fugl-Meyer motor functional assessment score and visual analog scale for assessment of pain and difficulties during active and passive range of motion were the other evaluation parameters. As a result, after botulinum toxin injection the spasticity decreased, active and passive range of motion, hand hygiene score, finger position score at rest, visual analogous scale and Fugl-Meyer motor functional assessment were improved significantly.